A recent clinical study showed that BC30™ (Heyndrickxia coagulans GBI-30, 6086), a spore-forming probiotic developed by Kerry Group, significantly improve gastrointestinal and digestive functions in healthy Chinese adults with irregular bowel movements.
The randomised, double-blind, placebo-controlled trial was conducted at the Beijing Institute of Geriatrics, Beijing Hospital, National Health Commission, China. Over a 28-day period, 111 healthy adults aged 18–65 consumed 1 billion CFU/day of BC30™ in a ready-to-mix nutritional sachet rehydrated in a beverage. Prior to the study, participants reported irregular bowel movements, defined as 4 or fewer bowel movements per week or 2 or more loose stools per week.
The following are the key findings of the study:
- Improved Digestive Function: Participants consuming BC30™ experienced a statistically significant increase in stool frequency and improved fecal consistency.
- Symptom Relief: Significant improvements were observed in overall GSRS (Gastrointestinal Symptom Rating Scale) scores, particularly in abdominal pain and constipation, during the final 2 weeks of the study.
- Microbiome Modulation: BC30™ intake led to increased levels of Bacteroides spp. and decreased levels of Clostridium spp., indicating positive modulation of the gut microbiota.
- Well-Tolerated: No adverse effects were reported, confirming BC30™’s safety and tolerability.
This study marks the first clinical validation of BC30™ in an Asian population, expanding the global relevance of its digestive health benefits. The trial was registered at ClinicalTrials.gov (NCT06644001) and published in Beneficial Microbes1.
Dr. Mathieu Millette, RDA Director, Digestive Health, Kerry mentioned that the study reaffirmed the versatility and afficacy of BC30™ across diverse populations.
With over 65 published studies, BC30™ is recognised for its stability, safety, and efficacy in digestive health and protein utilisation. It is U.S. FDA-notified GRAS and accepted by regulatory bodies globally.
BC30™ is part of Kerry’s portfolio of science-backed solutions tailored to meet digestive health needs of consumers around the world.
For more information, click on: Kerry Taste & Nutrition